Protein spills into urine, albumin drops, and swelling follows. Diagnosis relies on urine protein tests, low serum albumin, high lipids, renal function markers, and autoimmune panels. Ultrasound rules out structural issues, while biopsy confirms the exact pattern of glomerular injury. At Bhattacharjee’s Clinic, each case is mapped through inflammation, immunity, and metabolic terrain to pinpoint the true root.

Conventional treatment focuses on reducing protein loss, controlling inflammation, and preventing complications. Steroids are first-line for minimal-change disease, while FSGS or membranous cases may need immunosuppressants like calcineurin inhibitors or cyclophosphamide. Diuretics manage edema, ACE/ARB drugs reduce protein leakage, and statins stabilize lipid surges. Steroids and immunosuppressants can trigger weight gain, hypertension, diabetes, mood swings, infections, and long-term organ toxicity. Many patients relapse when medications are tapered, making remission unstable. ACE/ARB drugs may drop blood pressure excessively or raise potassium, limiting use in some cases. Diuretics can cause dehydration, electrolyte imbalances, and resistance over time. Most importantly, conventional care manages the symptoms but does not always address the underlying immune dysregulation or prevent progression in resistant cases like FSGS, leaving gaps in long-term healing.